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Crushed morphine sulfate CR significantly increased ratings of all positive subjective measures relative to placebo (P < 0.0001).Crushed MSN significantly decreased all positive subjective ratings compared with morphine sulfate CR (P ≤ 0.005), but significantly increased ratings compared with placebo (P < 0.03).Peak pupil diameter was significantly larger for MSN than morphine sulfate (P < 0 ...
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